32 SERIES (VIDEO 5)

hi everyone today we are going to discuss 32 important points from the topic oral aspects of metabolic diseases now these are important from need point of view now we shall see the very first point delayed eruption is seen in the following conditions such as rickets or vitamin D deficiency Down syndrome hypothyroidism Lido cranial dysplasia cherub ism and achondroplasia point number two Marrissa form xanthoma is a condition where presence of large for me cells in the connective tissue is seen between the papillae point number three human copper deficiency diseases of importance are hepatolan' ticular degeneration that is more often li called as wilson's disease and mink syndrome that is still e or kinky hair syndrome now the left corner image shows us the characteristic skin rash you - Gnaeus in deficiency especially in areas exposed to sunlight now this condition is called as castles necklace so that's going to be a fourth point now moving on to fifth point Addison's disease is due to insufficiency of adrenal cortex that shows deep chocolate pigmentation of oral mucosa point number six Cushing syndrome is produced by ACTH secreting tumors that also produced diffused mucocutaneous pigmentation similar to adrenal insufficiency point number seven the systemic disease that may increase oral male noses piece albright syndrome point number eight hypophosphite Asia is the condition where deficiency of enzyme alkaline phosphatase along with excretion of phosphorus an ala mine in urine and absence of cementum is seen whereas hypophosphatemia is vitamin D resistant rickets point number nine osteomalacia is a condition where is seen in newly-formed organic bone matrix point number 10 rickets is a condition where defect is seen in the mineralization of endochondral new pole point number 11 deficiency of vitamins a CD causes enamel hypoplasia point number 12 alcoholic patients with chronic thiamine deficiency shows CNS manifestations such as vernix encephalopathy now along with this if there is loss of memory as well it is known as vernix korok or syndrome now that's going to be a point number 13 now moving on to point number 14 in porphyria the sidious and permanent teeth may show a red or brownish discoloration and exhibit red fluorescence point number 15 her Lascelles or ghazal cells that is abnormal fibroblasts are the characteristic histological finding of furless syndrome whereas in cytoplasm of circulating lymphocytes we find metachromatic granules or rly bodies point number 16 claw hands broadening of mandible with a widened econo distance are features of hurler syndrome point number 17 draw a beefy tongue and ball tongue of Sandwich is associated with nian deficiency point number 18 magenta color tongue is associated with riboflavin deficiency point number 19 molars glossitis or hunters glossitis is associated with vitamin b12 deficiency point number 20 the old term histiocytosis X is replaced by new term called Langerhans cell histiocytosis that is LCH the presence of Burdick's granules is the characteristic finding in Langerhans cell histiocytosis point number 21 generalized gingival inflammation profuse elevation and scalding or skin from palm and foot is associated with Hey metal poisoning or toxicity now LED mercury bismuth and arsenic are the metals that cause heavy metal poisoning or toxicity these get deposited in the Ural tissues and extravasated in areas of chronic inflammation now additional to this the systemic signs and symptoms that may include our behavioral changes neurologic disorders intestinal pain and solarium join number 22 diabetes insipidus bone lesions and exophthalmos is seen in hand Sheila Christian disease point number 23 giant cells are characteristic histopathologic finding in the case of brown tumor of hyperparathyroidism point number 24 bone pain bone cyst fractures and renal stones are characteristics of hyperparathyroidism point number 25 hypogonadism developmental delay loss of taste and smell is due to deficiency of zinc point number 26 increase in height of mandible with increase in interdental spaces in elderly man is due to high particularism point number 27 the normal serum calcium level is 9 to 11 milligram percentage now point number 28 lamina dura is lost or partially lost in the case of hyperparathyroidism point number 29 tetiny is associated with a low concentration of ionized calcium in the serum point number 30 intestinal absorption of calcium is decreased by phytic acid point number 31 amyloid can be demonstrated by special stains like Congo red violet and high of Flavin tea fluorescent technique point number 32 Congo red staining is the gold standard for the diagnosis of amyloidosis biopsy is usually taken from the gingiva or the rectal tissue or any other suspected involved issue oh here amyloid shows apple-green birefringence under polarized light thank you